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慢阻肺病再现突破!GSK美泊利珠单抗III期研究成功

2024-09-10


9月6日,葛兰素史克(GSK)宣布Nucala(美泊利珠单抗)治疗慢性阻塞性肺病(简称慢阻肺病,COPD)的III期MATINEE研究取得了积极结果。该研究是一项为期52-104周的多中心、随机、双盲、安慰剂对照临床试验(n=806),评估了美泊利珠单抗(100mg,每4周1次,皮下注射)对比安慰剂作为疾病频繁恶化且血嗜酸性粒细胞水平升高的中度至重度COPD患者在维持治疗之外的附加治疗方案的有效性和安全性。研究的主要终点为中度至重度COPD的年恶化率

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